<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CMYD-96 04CMYD-96 Cameroon 2005 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35K, M36I, N37D, R41K, L63P, H69K, L89M  
>04CMYD-96| codons 10-99
LVTVKIGGQLIEALLDTGADDTVLEKIDLPGKWKPKMIGGIGGFIKVRQYDQIPIEICGK
KAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36D, T39A, E40D, K104R, K122E, D123S, I135T, S162A, K173T, Q174N, D177E, I178V, T200A, Q207A, R211K  
>04CMYD-96| codons 1-222
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICADMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTNNPEVVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQ

References
Author Title Citation
Ndembi, N Molecular characterization of human immunodeficiency virus type 1 (HIV-1) and HIV-2 in Yaounde, Cameroon: Evidence of major drug resistance mutations in newly diagnosed patients infected with subtypes other than subtype B. J Clin Microbiol, 2008