<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CMYD-52 04CMYD-52 Cameroon 2005 HIV1 CRF02_AG PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, N37D, R41K, L63H, H69K, K70R, I72M, L89M  
>04CMYD-52| codons 10-99
LVTVKIGGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIHIEICGK
RAMGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11A, E28K, K32E, V35T, E36D, S48E, K49R, V60I, D123E, S162A, K173T, Q174K, D177E, E194D, G196E, Q207E  
>04CMYD-52| codons 1-222
PISPIETVPVALKPGMDGPKVKQWPLTKEKIEALTDICTEMEKEGKIERIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLDIEQHRTKIEELREHLLRWGFTTPDKKHQ

References
Author Title Citation
Ndembi, N Molecular characterization of human immunodeficiency virus type 1 (HIV-1) and HIV-2 in Yaounde, Cameroon: Evidence of major drug resistance mutations in newly diagnosed patients infected with subtypes other than subtype B. J Clin Microbiol, 2008