Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1469 | CA9266 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | 3TC+AZT | 39 |
| 3 | 3TC+AZT+SQV | 17 |
| 4 | 3TC+AZT+IDV | 52 |
| 5 | D4T+DDI+NFV | 65 |
| 6 | 3TC+RTV+SQV | 18 |
| 7 | 3TC+RTV+SQV | 5 |
| 8 | 3TC+EFV+RTV+SQV | 7 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, T215F | K219EQ | L100I, K103N | V118I, K122E, I135T, I202V, H208Y, R211K, D218E, L228H, V245Q |
| >CA9266| codons 1-264 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKVEELRQYLLKWGFFTPEEKHQKEPPFHWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54S, V82A | M46V | L10I, G16A, N37D, L63P, A71I, V77I, I93L |
| >CA9609| codons 1-99 PQITLWQRPIVTIKIAGQLKEALLDTGADDTVLEEMDLPGRWKPKVIVGIGGFSKVRQYD QIPIEICGHKIIGTVLIGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |