<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T006 NPT6-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69DN, K70R, M184V, T215F K219E Y181C, G190A A98G V35T, E36A, T39E, S48T, V60I, K101Q, K104R, D121Y, K122E, I135L, K166R, K173A, D177E, T200A, Q207E, R211K, L228H, V245Q, A272P, K277R, E291D, V292I, I293V, Q334Y, G335D, R356K, G359N, T377M, K390R, E404D, Q428R, K431T, V435A, N447S, L452T, V466I, D471E, H483Y  
>NPT6-PL| codons 1-485
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLQKKRSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPEIVI
CQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYDQWTYQIYQEPFKNLKTGKYAKMRNA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP
PLVKLWYRLETEPIAGAETFYVDGAASRETKTGKAGYVTDRGRQKIVSLTETTNQKTELQ
AIYLA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14R, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
>NPT6-PL| codons 1-99
PQITLWQRPLVSIRIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007