<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T110 NPT110-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219Q K101E, G190A A98G K32E, V35K, E36A, T39D, I47IL, S48T, V60I, T69A, D121Y, K122E, I135K, S162A, K173T, Q174K, D177E, V179VI, T200A, E203K, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334N, G335D, K350R, R356K, G359T, T377M  
>NPT110-PL| codons 1-385
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIEALKAICDEMEKEGKLTKIGPENPYNTPI
FAIKKKNSARWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIII
YQYVDDLYVASDLEIGQHRAKIKELREHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLRTGKYAKMRTA
HTNDVKQLTEAVQKIAMESIVIWGK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L  
>NPT110-PL| codons 1-99
PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007