<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T083 NPT83-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210W, T215Y K219E Y181C, G190A   V35T, T39N, E44D, V60I, L109I, D121Y, K122E, I135T, S162A, K173A, Q174K, N175Y, D177E, T200A, Q207E, R211K, D218E, L228H, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, V317A, Q334E, R356K, G359T, E370A, A371V, T377M, K390R, A400T, E404D  
>NPT83-PL| codons 1-406
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNELEKDGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVIDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKYPEIVI
CQYVDDLYVASDLEIGQHRAKIEELREHLWKWGFYTPEEKHQKEPPFHWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTAVVQKIAMESIVIWGKTPKFRLPIQKETWETWWTDYW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, Q61E, L63P, H69K, L89M, I93L  
>NPT83-PL| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007