Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T109 | NPT109-PL | India | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V35T, T39N, S48T, V60I, D121H, K122E, S162SC, T165L, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277KR, E291D, V292I, I293V, P294T, G335D, R356K, M357R, G359T, A376AS, T377M, K390R, A400T, E404D |
| >NPT109-PL| codons 1-412 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMLKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKISMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15IV, L19I, M36I, N37D, R41K, D60E, L63T, H69K, K70R, L89M, I93L |
| >NPT109-PL| codons 1-99 PQITLWQRPLVSIRVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYE QITIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |