Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T108 | NPT108-PL | India | 2004 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210LW, T215Y | G190A | A98AG | V35T, V60I, D121H, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, V179I, G196K, Q197E, T200A, E203EK, Q207A, R211S, V245M, D250E, T286A, E291D, P294T, E312D, Q334N, G335D, M357Q, G359S, T369V, A371V, I375V, T377M, A400T |
| >NPT108-PL| codons 1-401 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYVDDLYVASDLEIKEHRAKIKELRAHLWSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVITLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYARQRSA HTNDVKQLVEVVQKVAMESIVIWGKTPKFKLPIQKETWETW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G16A, E35D, M36I, N37D, R41K, R57K, I62IV, H69K, L89M |
| >NPT108-PL| codons 1-99 PQITLWQRPLVTIKIAGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |