<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T108 NPT108-PL India 2004 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC|AZT|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210LW, T215Y   G190A A98AG V35T, V60I, D121H, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, V179I, G196K, Q197E, T200A, E203EK, Q207A, R211S, V245M, D250E, T286A, E291D, P294T, E312D, Q334N, G335D, M357Q, G359S, T369V, A371V, I375V, T377M, A400T  
>NPT108-PL| codons 1-401
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
YQYVDDLYVASDLEIKEHRAKIKELRAHLWSWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVITLTEEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYARQRSA
HTNDVKQLVEVVQKVAMESIVIWGKTPKFKLPIQKETWETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16A, E35D, M36I, N37D, R41K, R57K, I62IV, H69K, L89M  
>NPT108-PL| codons 1-99
PQITLWQRPLVTIKIAGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007