<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T101 NPT101-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67DN, M184V, T215F K70KQ V106A F227L T27TS, V35IT, T39N, V60I, D121Y, K122E, I142V, K173A, Q174R, D177E, I178L, T200A, E203A, Q207E, H208Y, R211K, K223KE, V245N, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297EK, L310I, E312Q, Q334H, G335D, R356K, M357MR, G359AT, V365VI, A371AV, T377Q, A400T, E404D  
>NPT101-PL| codons 1-406
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICNELEKEGKISKIGPENPYNTPI
FAIKKKNSTQWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPELVI
YQYVDDLYVGSDLEIGQHRAKIAELREYLLKWGFFTPDKKHQEEPPLLWMGYELHPDKWT
VQPINLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGAKALTDIVPLTKEAE
LELAENREIIKQPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDIKQLTEVVQKIAQESIVIWGKTPKFKLPIQKETWETWWTDYW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63T, H69K, L89M, I93L  
>NPT101-PL| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007