Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T113 | NPT113-PL | India | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|D4T|NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | N348I | Y181V | V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135T, K173A, Q174R, D177E, T200A, Q207E, F214L, V245Q, D256E, A272P, K277R, E291D, V292I, I293V, D324E, G335D, R356K, G359T, A376T, T377R, K390R, E396D, A400T, E404D |
| >NPT113-PL| codons 1-407 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI VQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNEIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKILKTGKYAKMRTA HTNDVKQLTEAVQKITRESIVIWGKTPKFRLPIQKDTWETWWTDYWQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15V, G17D, L19I, M36I, R41K, K45R, L63P, H69K, L89M, I93L |
| >NPT113-PL| codons 1-99 PQITLWQRPLVSIRVGDQIKEALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |