<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T111 NPT111-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|D4T|DDI|EFV|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, T215Y N348I Y188L   K20KR, V35T, T39D, E44D, S48T, V60I, V106VL, V118I, D121Y, K122E, I135T, S162A, K166R, K173T, D177E, T200A, Q207E, L210S, D218E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, T377I, K390R, A400T  
>NPT111-PL| codons 1-401
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICDELEKDGKITKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSLTVLDVGDAYFSIPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRTQNPEIVI
YQYVDDLLVGSDLEIGQHRAKIEELREHLSRWGFYTPEKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKILKTGKYAKMRTA
HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14R, I15V, L19T, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L  
>NPT111-PL| codons 1-99
PQITLWQRPLVSIRVGGQTKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007