Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T111 | NPT111-PL | India | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|D4T|DDI|EFV|NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | N348I | Y188L | K20KR, V35T, T39D, E44D, S48T, V60I, V106VL, V118I, D121Y, K122E, I135T, S162A, K166R, K173T, D177E, T200A, Q207E, L210S, D218E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, T377I, K390R, A400T |
| >NPT111-PL| codons 1-401 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICDELEKDGKITKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSLTVLDVGDAYFSIPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRTQNPEIVI YQYVDDLLVGSDLEIGQHRAKIEELREHLSRWGFYTPEKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKILKTGKYAKMRTA HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWETW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15V, L19T, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L |
| >NPT111-PL| codons 1-99 PQITLWQRPLVSIRVGGQTKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |