<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T107 NPT107-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L74V, M184V, L210W, T215F D67G, K219W, N348I Y181C, G190A   V35T, T39D, V60I, S68G, D121Y, K122E, K173A, Q174K, D177E, T200A, H208Y, R211K, L228H, E233D, V245Q, A272P, E291D, V292I, I293V, E297A, I326V, G335D  
>NPT107-PL| codons 1-354
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDELEKEGKISKIGPENPYNTPI
FAIKKKGGTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
CQYVDDLYVASDLEIGQHRAKIEELRQYLWKWGFFTPDWKHQKEPPFHWMGYDLHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKILKTGKY

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19T, E35D, M36I, R41K, L63P, H69K, I93L R87I
>NPT107-PL| codons 1-99
PQITLWQRPLVTIKIGGQTKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGINLLTQLGCTLNF

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007