<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
T023 NPT23-PL India 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC|D4T|NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19I, M36I, R41K, K45R, L63P, H69K, V82I, L89M, I93L  
>NPT23-PL| codons 1-99
PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39DE, S48T, V60I, D121Y, K122E, I135K, S162A, K173T, D177E, I178L, T200A, E204EK, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V317A, D324E, Q334N, G335D, Y342F, R356K, G359A, T377M, K390R, E404D, E432D, V435A, A437V, N447S, L452M, Q464E, V466I, D471E, T477A, H483Y  
>NPT23-PL| codons 1-484
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPELVI
YQYMDDLYVGSDLEIGQHRAKIEKLREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDVIPLTEEAE
LELAENREILKEPVHGAYYDPSKELIAEIQKQGNDQWTYQIFQEPFKNLKTGKYAKMRAA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGVETFYVDGAASRETKMGKAGYVTDRGREKIVSLTETTNQKAELQ
AIYL

References
Author Title Citation
Sen, S High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. ARHR, 2007