Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T100 | NPT100 | India | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, D60E, L63T, H69K, V82I, L89M, I93L |
| >NPT100| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QITIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, T215Y | K101E, G190A | T27S, E28K, V35T, T39D, S48T, V60I, D121H, K122E, I142V, K166R, D177E, I178F, I180V, T200A, Q207E, H208HY, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, G335D, Y342F, R356K, M357MR, G359T, T377M, K390R |
| >NPT100-PL| codons 1-401 PISPIETVPVKLKPGMDGPKVKQWPLSKEKIKALTEICDELEKEGKITKIGPENPYNTPI FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEFVV YQYVDDLYVASDLEIGQHRAKIEELREYLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIFQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKETWEAW |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |