Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| T076 | NPT76 | India | 2004 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|D4T|DDI|NFV|RTV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A, L90M | T74P | L10V, T12A, I15V, L19I, K20R, M36I, N37D, K55N, L63P, H69K, A71V, I93L |
| >NPT76| codons 1-99 PQITLWQRPVVAIKVGGQIREALLDTGADDTVLEEIDLPGRWKPKLIGGIGGFINVRQYD QIPIEICGKKVIGPVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, L74V | D67G, K219Q | V35T, E36A, T39D, S48T, K64N, D121Y, K122E, I135T, T165I, R172K, K173A, Q174R, D177E, I178L, T200A, E203K, Q207E, R211K, F214L, D218E, Q242QK, V245Q, A272P, K277R, L283I, I293V, G335D, R356K, G359AT, A360AT, V365VI, K390KR, A400T, E404D |
| >NPT76-PL| codons 1-406 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAINKKGSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFKARNPELVI YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGLTTPEQKHQKEPPFLWMGYELHPDKWT VKPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTT HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWETWWTDYW |
References
| Author | Title | Citation |
| Sen, S | High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India. | ARHR, 2007 |