Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3986 | CA9236 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 43 |
| 2 | 3TC+AZT+DDC | 61 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+D4T+IDV | 57 |
| 5 | DDI+NFV+NVP | 67 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | K20R, K49R, K104R, K122E, I135T, S162SN, Q207E, H221HY |
| >CA9236| codons 1-258 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10LF, N88D | T12D, K14R, E35D, M36I, I62V, L63P, A71I, I85IV, I93L | G17GV |
| >CA9566| codons 1-99 PQITLWQRPFVDIRIGVQLKEALLDTGADNTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKIIGTVLVGPTPVNIVGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |