<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1410 CA9223 U.S. 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+DDC+DLV+NFV 26
2 D4T+DLV+NFV 24
3 3TC+D4T+IDV+NFV 87

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, M184V T215V, K219*QRW Y181YC V179D K20R, V35M, K43KE, K103R, V118VI, S162G, K166T, G196E, Q207E, F214L, L228H  
>CA9223| codons 1-259
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTELEEEGKISKIGPENPYNTPV
FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQGSMTTILEPFRKQNPDIDI
CQYVDDLYVGSDLEIEQHRTKIEELREHLLRWGLVTPDWKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M G73T L10I, N37H, I62V, L63P, I64IV, V77I, I93L  
>CA9840| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMHLPGRWKPKMIGGIGGFIKVRQYD
QVPVEICGHKAITTVLIGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005