Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1461 | 1461b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 56 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | I37X, D123E, I135V, K173E, D177E, H221Y, V245Q |
| >1461b| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGS PAIFQSSMTKILEPFREQNPEIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTT PDKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| P39S, R41K, D60E, L63P, A71T, V77I |
| >1461b| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLSGKWKPKMIGGIGGFIKVRQYEQIP IEICGHKTIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |