Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1744 | 1744b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 48 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K101E, K103N | D123E, I142V, T200E, Q207G, V245K |
| >1744b| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHREKIEELRGHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, E35D, K43R, I62V, L63P, L90LF, I93L |
| >1744b| codons 4-99 TLWQRPLVAVKIGGQLKEALLDTGADDTVLEDMNLPGRWRPKMIGGIGGFIKVRQYDQVP IEICGHKAIGTVLVGPTPVNIIGRNLFTQLGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |