Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2288 | 2288c | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 57 |
| 2 | 3TC+AZT+NFV | 30 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L63P, V77I, I93L |
| >2288c| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V75I | K103N | D123E, K173Q, I178L, Q207K, R211K, F214L, L228Q | S105SL |
| >2288c| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHP AGLKKNKLVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRQQNPDLVIYQYVDDLYVGSDLEIGQHRTKIEELRKHLLKWGLTTP DKKHQKEPPFQWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |