Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JIDP20 | JIDP20W104 | U.S. | 1993 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | AZT+ DDI | 104 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | E44D, V60I, V118I, K122E, A158S, G196E, V241X, V245T |
| >JIDP20W104| codons 26-245 LTEEKIKALVEICTELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQ DFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQ YNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRTKIEEL RQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWTXQPIT |
References
| Author | Title | Citation |
| Shafer, RW | Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type 1 - infected subjects to zidovudine and didanosine combination therapy. | J Infect Dis, 1995 |
| Shafer, RW | Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations. | J Infect Dis, 1994 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |