Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_5951 | 5951c | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 26 |
| 2 | D4T+DDI+NFV | 10 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I62IV, L63T, I64L, V77I |
| >5951c| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVTLEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K20R, V35M, D123E, I142IV, D177E, G196E, Q207QR, F214L, L228LHQ, K277R |
| >5951c| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIEQHRTKIEELRRHLLRWGLTTPDKKHQKEPPFQWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |