Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_4079 | 4079b | U.S. | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NFV | 30 |
| 2 | 3TC+AZT+EFV | 1 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | L33LF | L10I, I15V, K20KT, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, L89M |
| >4079b| codons 1-99 PQITLWQRPIVTIKVGGQLTEALLDTGADDTVFEDINLPGKWKPKMIGGIGGFIKVKQYD NITIDICGHKAIGTVLVGPTPVNIIGRSMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR | D67DG | V35T, K49R, V106VI, K122KE, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211RK, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, S322T |
| >4079b| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV FAIKRKGSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPTKD |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |