Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1464 | 1464b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV+NFV | 19 |
| 2 | None | 3 |
| 3 | D4T+DDI+EFV+NFV | 20 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L33LF | W6WS, I62V, L63P, I64L |
| >1464b| codons 4-99 TLSQRPLVTIKIGGQLKEALLDTGADNTVFEEMNLPGRWKPKMIGGIGGFIKVRQYDQVP LEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75VI | K103N, Y188YH | P225PH | I37X, R83K, D121Y, K122E, G196E, R211K, I244V, V245T |
| >1464b| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLIDFRELNKKTQDFWEVQLGIPH PAGLKKNKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PAIFQSSMTKILEPFRKQNPDIVIYQYMDDLHVGSDLEIEQHRTKIEELRQHLLKWGFTT PDKKHQKEHPFLWMGYELHPDKWTVQPVTLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |