Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2531 | 2531a | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, M36I, N37D, L38LF, L63V, I93L |
| >2531a| codons 4-99 TLWQRPLVAIKIGGQLKEALLDTGADDTVLEEIDFPGRWKPKMIGGIGGFIKVRQYDQIV IEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I37X, R83K, K122E, E169D, T200E, Q207K, V245M | T107TK |
| >2531a| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPH PAGLKKKKSVKVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PAIFQSSMTKILDPFRKQNPDIVIYQYMDDLYVGSDLEIGQHREKIEELRKHLLRWGFTT PDKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |