Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_3918 | 3918c | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 19 |
| 2 | D4T+DDI+EFV | 21 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12S, N37C, I62V, L63C |
| >3918c| codons 4-99 TLWQRPIVSIKIGGQLKEALLDTGADDTVLEEMCLPGRWKPKMIGGIGGFIKVRQYDQVC IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N, V106A | P225H | I37X, K122E, I135V, I142V, D177E, G196R, T200A, R211K |
| >3918c| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLKKNKSATVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGS PAIFQSSMTKILEPFRKQNPEIVIYQYMDDLYVGSDLEIRQHRAKIEELRQHLLKWGFTT PDKKHQKEHPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |