Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_3918 | 3918b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 19 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| W6WG, L10V, T12P, N37CS, I62V, L63AS, I64M | D29DV |
| >3918b| codons 4-99 TLGQRPVVPIKIGGQLKEALLDTGAVDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQVS MEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103T | I37X, K122E, I135V, I142IV, D177E, G196GR, T200TA, R211K |
| >3918b| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLKKTKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGS PAIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIRQHRAKIEELRQHLLKWGFTT PDKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |