<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
A384_5611 5611a U.S. 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15IV, M36L, N37D, R57K, I62V, L63HQ, A71V, I93L, F99X  
>5611a| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGADDTVLEELDLPGRWKPKMIGGIGGFIKVKQYDQVQ
IEICGHKVIGTVLVGPTPVNIIGRNLLTQLGCTLNL

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I37X, K101KR, K122A, I142IV, K166R, I178M, Q207E, R211K  
>5611a| codons 37-247
VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH
PAGLRKKKSVTVLDVGDAYFSVPLDADFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGS
PAIFQSSMTRILEPFRKQNPDMVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTT
PDKKHQKEPPFLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Shafer, RW Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med, 2003