Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0086 | 0086b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 24 |
| 2 | Unknown | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, L74LV | K103N, G190S | S68SG, V90I, G196GR, R211K, V245L |
| >0086b| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKRKDGTKWRKVVDFRELNKRTQDFWEIQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVSSDLEIRQHRTKIEELRQHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPILLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, R57RK, I62IV, I64V |
| >0086b| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYDQVL VEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |