Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0074 | 0074c | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 72 |
| 2 | 3TC+AZT+NFV | 17 |
| 3 | None | 3 |
| 4 | 3TC+AZT+NFV | 14 |
| 5 | None | 2 |
| 6 | 3TC+AZT+NFV | 2 |
| 7 | Unknown | 10 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV, L210LW, T215TNSY | L100I, K103N | V60VI, V118VI, I142V, A158AS, S162SAGT, P170PT, N175NH, Q197QR, T200TA, Q207QE, R211K, E224EG, L228LR, V245E | K65KQ |
| >0074c| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKQKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP SIFQTSMTKILETFRKQHPDIVIYQYVDDLYVGSDLEIGRHRAKIEELREHLWKWGFYTP DKKHQKGPPFRWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36MI, R41RK, F99X |
| >0074c| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNL |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |