Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0787 | 0787b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV+NFV | 35 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, K20R, N37D, D60E, L63P |
| >0787b| codons 4-99 TLWQRPLVAIKIGGQLREALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYEQIP IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | T39S, R83K, D123E, I135T, Q174G, G196E, P243S, V245E | H96HN, D113DN |
| >0787b| codons 38-247 CSEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPNP AGLKKNKSVTVLDVGNAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKGNPDIVIYQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQSIELP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |