Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_3441 | 3441b | U.S. | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, M36L, R41K, L63P, H69K, I93L |
| >3441b| codons 4-99 TLWQRPLVSIKVGGQTREALLDTGADDTVLEELNLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T39EG, S48T, A98AS, K122E, I135R, K173A, Q174K, D177E, I202V, Q207K, R211K, V245Q |
| >3441b| codons 38-246 CGEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAKNPEIVIYQYMDDLYVGSDLEIGQHRTKVEELRKHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQL |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |