Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1145 | 1145b | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NFV | 25 |
| 2 | None | 7 |
| 3 | D4T+DDI+NFV | 42 |
| 4 | None | 6 |
| 5 | D4T+DDI+NFV | 53 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI | W6WR, L10I, E35D, M36MI, D60DE, I62IV, L63T, E65D, A71AV |
| >1145b| codons 4-99 TLRQRPIVTIKIGGQLKEALLDTGADDTILEDINLPGRWKPKMIGGIGGFIKVRQYEQVT IDICGHKVIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DG | K104KQ, V245Q |
| >1145b| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKGSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKQSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |