Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0380 | 0380b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV+NFV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14KR, K20R, E35ED, N37S, L63P |
| >0380b| codons 1-99 PQITLWQRPLVTIRIGGQLREALLDTGADDTVLEDMSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20KR, V90VI, I142V, S162A, T200A, K249KQ, A272P, V276I, K277R, T286A |
| >0380b| codons 1-291 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEQDSWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTE |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |