Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0378 | 0378b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 26 |
| 2 | None | 7 |
| 3 | D4T+DDI+EFV | 9 |
| 4 | 3TC+AZT+EFV | 8 |
| 5 | EFV+RTV+SQV | 1 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190S | I37X, D123E, Q207E, R211K |
| >0378b| codons 37-247 VCTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLEKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVSSDLEIGQHRTKIEELREHLLKWGFTT PDKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14KR, Q18QH, L63P, I72V |
| >0378b| codons 4-99 TLWQRPLVTIRIGGHLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |