Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_7259 | 7259b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NFV | 29 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, L90LM | W6WR, I15V, K20T, E35D, M36I, D60E, I62V, V82I |
| >7259b| codons 1-99 PQITLRQRPLVTIKVGGQLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFLKVRQYE QVLIEICGHKAIGTVLVGPTPINIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D121C, K122E, K166R, E204Q, Q207E, R211K, F214L | Q182QL |
| >7259b| codons 1-236 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL CEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI YLYMDDLYVGSDLEIGQHRTKIEQLREHLLKWGLTTPDKKHQKEPPFLWMGYELHP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |