Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1478 | 1478b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 8 |
| 2 | None | 3 |
| 3 | 3TC+D4T+NFV | 15 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33V, E35D, N37S, L63P, I64V, V82VI, I93L |
| >1478b| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVVEDMSLPGRWKPKMIGGIGGFIKVRQYDQIP VEICGHKAIGTVLVGPTPINIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | F87FS, K102Q, V111VL, D123DG, S134SG, S162C, E203D, R211K |
| >1478b| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDSWEVQLGIPHP AGLKQKKSVTVLDLGDAYFSVPLDKGFRKYTAFTIPGINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIDELRQHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |