Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_3628 | 3628b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 47 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V | L100I, K103N, G190A | F87L, D121H, K122E, Q197L, T200E, E204K, R211K, F214L, V245M |
| >3628b| codons 39-245 TEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDLWEVQLGIPHPA GIKKNKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPA IFQSSMTKILEPFRKQNPDIVIYQYMDDLYVASDLEIGLHREKIEKLRQHLLKWGLTTPD KKHQKEPPFLWMGYELHPDKWTVQPIM |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G16X, P39A, R41K, L63P, V77I, I93L |
| >3628b| codons 4-99 TLWQRPLVTIKIWGQLKEALLDTGADDTVLEEMNLAGKWKPKMIGGIGGFIKVRQYDQIP IEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |