Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2774 | 2774a | U.S. | 1999 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| P9X, E35D, M36I, R41K, R57K, I62V, L63I, H69K, L89IM, F99X |
| >2774a| codons 5-99 LWQRTLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDQVII EICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNL |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E40D, V60I, K64R, V111VL, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200TA, Q207A, R211S, V245M | D76DN, D110DN, D113DN |
| >2774a| codons 38-246 CTDMEKEGKISKIGPENPYNTPIFAIRKKDSTKWRKLVNFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLNLGNAYFSVPLHESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRSKNPEIIIYQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIML |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |