Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2757 | 2757b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 20 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | I13V, L19I, K20T, E35D, N37D, R57K, L63P, I64V, V77I |
| >2757b| codons 1-99 PQITLWQRPLVTVKIGGQITEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVKQYD QIPVEICGHKAIGTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20R, V35IT, V60I, R83K, I135T, N175H, G196E, T200A, R211K, L228H, T286A, A288S, V292I | A267AS |
| >2757b| codons 1-295 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQHPDIVI YQYVDDLYVGSDLEIEQHRAKIEELRQHLLKWGFTTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWSSQIYAGIKVKQLCKLLRGAKSLTEIIPL |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |