Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2749 | 2749b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV+NFV | 24 |
| 2 | None | 6 |
| 3 | 3TC+AZT+EFV+NFV | 12 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V108I | K32Q, E36ED, W88S, K101Q, D123E, I135K, S163SC, K166R, D177E, I202V, R211K, H221Y, V245E | R143RS |
| >2749b| codons 1-257 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIQALVDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLQKNKSVTILDVGDAYFSVPL DKEFRKYTAFTIPSKNNETPGISYQYNVLPQGWKGSPAIFQSCMTRILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12KN, K43KN, L63P |
| >2749b| codons 1-99 PQITLWQRPLVNIKIGGQLKEALLDTGADDTVLEEMNLPGRWNPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |