Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1082 | 1082d | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 22 |
| 2 | 3TC+AZT+NFV | 32 |
| 3 | IDV+RTV | 1 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M | F116Y | K103N, Y188L | I37X, V60I, S68SR, R83K, K102R, D123E, I135V, R172K, I178L, R211RK, V245D |
| >1082d| codons 37-247 VCTEMEKEGKISKIGPENPYNTPIFAIKRKDRTKWRKLVDFRELNKKTQDFWEVQLGIPH PAGLKRNKSVTVLDVGDAYYSVPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGS PAIFQSSMTKILEPFKKQNPDLVIYQYMDDLLVGSDLEIGQHRTKIEELRQHLLKWGFTT PDKKHQKEPPFLWMGYELHPDKWTVQPIDLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, L90LIM | L10I, E35D, L38LW, K45KR, L63P, I64L, H69Q, A71AT |
| >1082d| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADNTVLEDMNWPGRWKPRMIGGIGGFIKVRQYDQIP LEICGQKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |