Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_1082 | 1082c | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+EFV | 22 |
| 2 | 3TC+AZT+NFV | 32 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M | F116Y | K103N, Y188L | V35M, V60I, S68R, R83K, K102R, D123E, I135V, R172K, I178L |
| >1082c| codons 1-236 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPI FAIKRKDRTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKRNKSVTVLDVGDAYYSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFKKQNPDLVI YQYMDDLLVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, L90LIM | L10I, E35D, K45KR, L63P, I64L, H69Q, A71AT |
| >1082c| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADNTVLEDMNLPGRWKPRMIGGIGGFIKVRQYD QIPLEICGQKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |