Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_4002 | 4002b | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 71 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V | S48T, K122Q, S162H, D177E, V179I, E194EG, G196E, Q207G, R211K, P243A |
| >4002b| codons 38-247 CTEMEKEGKITKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDQDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQHSMTKILEPFRKQNPEIIIYQYVDDLYVGSDLGIEQHRTKIEELRGHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQAIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20T, M36I, R41K, D60E, I62V, I64V, I93L |
| >4002b| codons 4-99 TLWQRPLVTVRIGGQLTEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEQVL VEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |