Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2043 | 2043b | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 30 |
| 2 | None | 14 |
| 3 | 3TC+AZT+LPV | 5 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TA, K20R, M36I, N37S, I62V, L63H, I64V |
| >2043b| codons 4-99 TLWQRPLVAIKIGGQLREALLDTGADDTVLEEISLPGRWKPKMIGGIGGFIKVRQYDQVH VEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V60I, W88WC, V118VI, I135IV, A158S, K166R, I180V, I202V, R211K |
| >2043b| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP SIFQSSMTRILEPFRKQNPDIVVYQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |