Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2105 | 2105b | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+NFV | 11 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19LI, M36MI, N37D, I62V, L63S, Q92K |
| >2105b| codons 4-99 TLWQRPLVTIKIGGQIKEALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFIKVRQYDQVS IEICGHKAIGTVLVGPTPVNIIGRNLLTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V118I, K122KR, D123E, I142V, T165I, Q174R, T200A, R211G, F214L |
| >2105b| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDREFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMIKILEPFRKRNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLGWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |