Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0901 | 0901d | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 16 |
| 2 | D4T+DDI+EFV | 26 |
| 3 | 3TC+APV+D4T+EFV+RTV | 40 |
| 4 | 3TC+ABC+APV+EFV+RTV | 104 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, I84V, L90M | L33F, N83D | L10I, K20R, E35N, M36L, N37D, I62V, L63P, A71V, L89I |
| >0901d| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVFENLDLPGRWKPKMIGGIGGFLKVRQYD QVPIEICGHKVIGTVLVGPTPVDVIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | K101E, G190S | P4PS, E6KR, V35I, T39S, K43Q, E44D, D121DH, K122E, D123X, V179I, Q197K, T200A, I202V, H208Y, R211K, H221Y, A288S, I293V, E297K |
| >0901d| codons 1-298 PISSIRTVPVKLKPGMDGPKVKQWPLTEEKIKALIEICSELEQDGKISKIGPENPYNTPV FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL HEXFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVSSDLEIGKHRAKVEELRQYLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTKE |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |