Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_0901 | 0901c | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 16 |
| 2 | D4T+DDI+EFV | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | N83D | L10I, K20R, E35D, M36I, N37D, I62V, L63P, A71V |
| >0901c| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVRQYDQVP IEICGHKVIGTVLVGPTPVDVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, L210W, T215Y | V106A, G190S | T39S, K43Q, E44D, V118I, K122E, D123N, V179I, Q197K, T200A, I202V, H208Y, R211K, H221Y | R83EK |
| >0901c| codons 38-247 CSELEQDGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKKTQDFWEVQLGIPHP AGLKKKKSATVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVSSDLEIGKHRAKVEELRQYLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |