Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PO-Pt21 | Orl21-W272 | Italy | 1995 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 272 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215V, K219Q | T39A, D123E |
| >Orl21-W272| codons 3-220 SPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPVFA IKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDK EFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQ YMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFVTPDQK |
References
| Author | Title | Citation |
| Orlandi, P | Analysis of HIV-1 reverse transcriptase gene mutations in infected children treated with zidovudine. | JAIDS, 1998 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |