Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A384_2436 | 2436d | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 50 |
| 2 | D4T+DDI+EFV | 22 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N, M230ML | K238T | S48T, E79D, I178L, V179VI, H208HY, R211K, V245EK, E248D, A272P, K277R, I293V, T296S |
| >2436d| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRDLNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLII YQYVDDLYVGSDLEIGQHRTKIEELRQYLLKWGFTTPDKKHQKEPPFLWLGYELHPDTWT VQPIKLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLSEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, E35D, N37S, L63P, I72M, V77I | T26TA |
| >2436d| codons 9-99 PLVSIKIGGQIKEALLDAGADDTVLEDMSLPGRWKPKMIGGIGGFIKVRQYDQIPIEICG HKAMGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Shafer, RW | Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. | N Engl J Med, 2003 |